Novel Dexamethasone-Loaded Nanomicelles for the Intermediate and Posterior Segment Uveitis
نویسندگان
چکیده
منابع مشابه
Vision-related functioning outcomes of dexamethasone intravitreal implant in noninfectious intermediate or posterior uveitis.
PURPOSE To evaluate the effect of a single treatment with dexamethasone intravitreal implant (DEX implant) on patient-reported visual functioning in patients with noninfectious intermediate or posterior uveitis. METHODS Patient eyes with noninfectious intermediate or posterior uveitis were randomized to a single treatment with DEX implant 0.70 mg (n=77), DEX implant 0.35 mg (n=76), or a sham ...
متن کاملDexamethasone implants in paediatric patients with noninfectious intermediate or posterior uveitis: first prospective exploratory case series
BACKGROUND To evaluate the efficacy and safety of dexamethasone (DEX) implants in paediatric patients with noninfectious intermediate or posterior uveitis. METHODS Prospective single center exploratory case series. Children and adolescents, 6 to 17 years old, with a vitreous haze score of ≥1.5+ or cystoid macular edema (CME) of >300 μm were enrolled. Vitreous haze score at month 2 was chosen ...
متن کاملCyclosporine vs tacrolimus therapy for posterior and intermediate uveitis.
OBJECTIVES To compare the efficacy and tolerability of tacrolimus and cyclosporine therapy for noninfectious posterior segment intraocular inflammation and to evaluate their effect on peripheral blood CD4(+) T-cell phenotype and activation status. METHODS Thirty-seven patients who required second-line immunosuppression for posterior segment intraocular inflammation were enrolled in this prosp...
متن کاملNovel Intraocular Therapy in Non-infectious Uveitis of the Posterior Segment of the Eye
This article reviews the new clinically relevant data regarding the intraocular treatment of non-infectious uveitis. Triamcinolone acetonide is the most commonly used intravitreal corticosteroid for treatment of uveitis and uveitic macular oedema. The drug is available at low cost but it is associated with a high risk of raised intraocular pressure (IOP) and cataract and is not licensed for int...
متن کاملIntermediate uveitis, posterior uveitis, and panuveitis in the Mid-Atlantic USA
BACKGROUND The purpose of this study was to identify the causes, clinical features, and outcomes of intermediate uveitis, posterior uveitis, and panuveitis in patients managed in a mid-Atlantic tertiary care center. METHODS This was a retrospective observational study of intermediate uveitis, posterior uveitis, and panuveitis patients seen at the University of Virginia from 1984 to 2014. RE...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2014
ISSN: 1530-9932
DOI: 10.1208/s12249-014-0100-4